Across TCGA patient cohorts, TBC1D28 mutation is significantly associated with the RNA expression of many other genes, with 759 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D28-associated genes across cancer lineages are SLC25A6P6, MTND1P4, and MIR194-1. Each is linked with TBC1D28 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D28-to-partner and partner-to-TBC1D28 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D28→partner) and Y-score (partner→TBC1D28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SLC25A6P6 →	+0.074	+6.584	<.001	.001	3	2
LUSC	MTND1P4 →	+0.166	+6.210	<.001	<.001	3	2
UCEC	MIR194-1 →	+0.735	+2.501	<.001	.007	3	2
UCEC	HSPE1-MOB4 →	+0.177	+3.016	.004	.002	3	1
UCEC	GPR75-ASB3 →	+0.147	+4.083	<.001	<.001	3	1
UCEC	SPDYE19P →	+0.251	+4.026	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 759 associations by consensus.

Exploration

TBC1D28 survival (RNA) · tumor vs normal (RNA) · all TBC1D28 data types