TBC1D26

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TBC1D26 mutation is significantly associated with the RNA expression of many other genes, with 80 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible TBC1D26-associated genes across cancer lineages are MIR4688, TYRL, and OR2AT2P. Each is linked with TBC1D26 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D26-to-partner and partner-to-TBC1D26 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D26→partner) and Y-score (partner→TBC1D26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCMIR4688 →+0.411+4.705<.001.00332
LIHCTYRL →+0.900+5.878<.001.00232
LIHCOR2AT2P →+0.052+5.355<.001.00532
COADMIR1179 →+1.171+7.741<.001.00932
UCECPPP1R12BP1 →+0.037+5.582.001.00232
SKCMRNU6-1067P →+0.371+3.330<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 80 associations by consensus.

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