TBC1D22B

Across TCGA cell cohorts, TBC1D22B mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TBC1D22B-associated genes across cancer lineages are ZNF705G, IQCM, and OR52E5. Each is linked with TBC1D22B in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D22B-to-partner and partner-to-TBC1D22B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF705G grouped by TBC1D22B-low versus TBC1D22B-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D22B→partner) and Y-score (partner→TBC1D22B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ZNF705G →	+0.006	+4.922	.005	.009	3	1
BLOOD_Leukemia	IQCM →	+0.045	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR52E5 →	+0.016	+5.539	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ZNF705G by TBC1D22B expression — BLOOD_Leukemia

Explore this box plot interactively →