TBC1D22A

Across TCGA patient cohorts, TBC1D22A protein abundance is significantly associated with the RNA expression of many other genes, with 13,521 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TBC1D22A-associated genes across cancer lineages are ARFGAP3, PACSIN2, and KIAA0930. Each is linked with TBC1D22A in more than 5 cancer types. Because this analysis shows association rather than direction, both TBC1D22A-to-partner and partner-to-TBC1D22A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D22A versus ARFGAP3 in OV, with a Pearson correlation of 0.55.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D22A→partner) and Y-score (partner→TBC1D22A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ARFGAP3 →	+0.910	+0.349	<.001	<.001	3	6
OV	PACSIN2 →	+0.902	+0.369	<.001	<.001	3	5
GBM	KIAA0930 →	+0.660	+0.273	<.001	<.001	3	5
LSCC	ZNF768 →	-0.538	-0.175	.003	.006	3	5
GBM	ZNF3 →	-0.520	-0.229	<.001	<.001	3	4
OV	TOM1 →	+0.627	+0.305	.003	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,521 associations by consensus.

TBC1D22A vs ARFGAP3 — OV

Explore this scatter interactively →