TBC1D20

Across TCGA patient cohorts, TBC1D20 mutation is significantly associated with the RNA expression of many other genes, with 4,240 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D20-associated genes across cancer lineages are ZNF736P6Y, RN7SL248P, and RNU1-14P. Each is linked with TBC1D20 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D20-to-partner and partner-to-TBC1D20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF736P6Y grouped by TBC1D20-low versus TBC1D20-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D20→partner) and Y-score (partner→TBC1D20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ZNF736P6Y →	+0.039	+4.970	.001	.005	3	2
CESC	RN7SL248P →	+0.096	+6.000	<.001	<.001	3	2
COAD	RNU1-14P →	+0.664	+4.070	<.001	.009	3	2
CESC	RNA5SP198 →	+0.224	+4.559	<.001	.006	3	2
UCEC	MIR6857 →	+0.175	+2.136	.003	.003	3	2
UCEC	RNU6-13P →	+0.176	+1.684	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,240 associations by consensus.

ZNF736P6Y by TBC1D20 expression — SKCM

Explore this box plot interactively →