TBC1D2

Across TCGA patient cohorts, TBC1D2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,790 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TBC1D2-associated proteins across cancer lineages are TBC1D2_S920, CORO2A, and FAM120A. Each is linked with TBC1D2 in more than 5 cancer types. Because this analysis shows association rather than direction, both TBC1D2-to-partner and partner-to-TBC1D2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D2 versus TBC1D2_S920 in CCRCC, with a Pearson correlation of 0.57.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D2→partner) and Y-score (partner→TBC1D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	TBC1D2_S920 →	+0.686	+1.007	<.001	<.001	3	6
OV	CORO2A →	+0.628	+1.049	<.001	<.001	3	6
BRCA	FAM120A →	+0.196	+0.657	.002	<.001	3	5
BRCA	GOLGA1 →	+0.250	+0.546	<.001	<.001	3	5
PDAC	TBC1D2_S436 →	+1.138	+1.437	<.001	<.001	3	5
OV	NIBAN2 →	+0.450	+0.850	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,790 associations by consensus.

TBC1D2 vs TBC1D2_S920 — CCRCC

Explore this scatter interactively →