TBC1D19

Across TCGA patient cohorts, TBC1D19 mutation is significantly associated with the RNA expression of many other genes, with 1,885 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D19-associated genes across cancer lineages are IGLV3-31, LINC01103, and ACTRT2. Each is linked with TBC1D19 in more than 2 cancer types. Because this analysis shows association rather than direction, both TBC1D19-to-partner and partner-to-TBC1D19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IGLV3-31 grouped by TBC1D19-low versus TBC1D19-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D19→partner) and Y-score (partner→TBC1D19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IGLV3-31 →	+0.192	+1.771	.007	.001	3	3
BLCA	LINC01103 →	+0.046	+5.788	<.001	.003	3	2
READ	ACTRT2 →	+0.102	+6.257	<.001	.001	3	2
CESC	MIR3661 →	+0.313	+4.539	<.001	.008	3	2
CESC	MIR6816 →	+0.435	+5.144	<.001	.003	3	2
COAD	OR13Z1P →	+0.139	+4.308	.002	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,885 associations by consensus.

IGLV3-31 by TBC1D19 expression — UCEC

Explore this box plot interactively →