TBC1D16

Across TCGA patient cohorts, TBC1D16 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,990 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TBC1D16-associated proteins across cancer lineages are ISG20, XAF1_S268, and MINK1. Each is linked with TBC1D16 in more than 5 cancer types. Because this analysis shows association rather than direction, both TBC1D16-to-partner and partner-to-TBC1D16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D16 versus ISG20 in BRCA, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D16→partner) and Y-score (partner→TBC1D16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ISG20 →	-0.689	-0.705	<.001	<.001	2	6
GBM	XAF1_S268 →	-0.599	-0.331	.001	.001	3	5
HNSC	MINK1 →	-0.303	-0.581	.001	.008	2	5
LSCC	ZMYM3_S464 →	+0.532	+0.732	<.001	<.001	3	4
LSCC	LSP1_S139 →	-0.700	-0.480	<.001	.002	3	4
COAD	APBB2 →	+0.470	+0.686	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,990 associations by consensus.

TBC1D16 vs ISG20 — BRCA

Explore this scatter interactively →