TBC1D13

Across TCGA patient cohorts, TBC1D13 mutation is significantly associated with the RNA expression of many other genes, with 2,833 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D13-associated genes across cancer lineages are CENPU, TRIM17, and ZNF367. Each is linked with TBC1D13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D13-to-partner and partner-to-TBC1D13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPU grouped by TBC1D13-low versus TBC1D13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D13→partner) and Y-score (partner→TBC1D13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPU →	+0.731	+3.584	.002	.002	3	2
UCEC	TRIM17 →	-1.448	-2.764	<.001	.003	3	2
UCEC	ZNF367 →	+1.156	+4.087	<.001	<.001	3	2
UCEC	NDRG2 →	-1.098	-3.568	<.001	.002	3	2
UCEC	C5orf22 →	+0.631	+3.606	.001	.001	3	2
UCEC	PACSIN2 →	+0.563	+2.606	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,833 associations by consensus.

CENPU by TBC1D13 expression — UCEC

Explore this box plot interactively →