TBC1D13

Across TCGA patient cohorts, TBC1D13 mutation is significantly associated with the total protein of many other genes, with 12 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TBC1D13-associated genes across cancer lineages are eIF4E, FoxM1, and Myosin-IIa_pS1943. Each is linked with TBC1D13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D13-to-partner and partner-to-TBC1D13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by TBC1D13-low versus TBC1D13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D13→partner) and Y-score (partner→TBC1D13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.204	+3.321	.038	.010	3	1
UCEC	FoxM1 →	+0.254	+2.584	.035	.011	3	1
UCEC	Myosin-IIa_pS1943 →	+0.217	+1.887	.024	.031	3	1
UCEC	p62 Lck ligand →	+0.495	+2.331	.001	.019	3	1
UCEC	Paxillin →	+0.333	+2.584	.005	.011	3	1
UCEC	PCNA →	+0.242	+2.321	.016	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

eIF4E by TBC1D13 expression — UCEC

Explore this box plot interactively →