TBC1D10C

Across TCGA cell cohorts, TBC1D10C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,683 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TBC1D10C-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Negative regulation of myoblast fusion, and Cilium-dependent cell motility. Each is linked with TBC1D10C in more than 14 cancer types. Because this analysis shows association rather than direction, both TBC1D10C-to-partner and partner-to-TBC1D10C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by TBC1D10C-low versus TBC1D10C-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D10C→partner) and Y-score (partner→TBC1D10C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.161	+0.858	<.001	<.001	3	15
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.159	+0.804	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.113	-0.536	<.001	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.113	-0.536	<.001	.003	3	14
OESOPHAGUS	Regulation of myoblast fusion →	+0.145	+0.797	<.001	<.001	3	14
BONE	Protein localization to cytoplasmic stress granule →	+0.172	+0.924	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,683 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by TBC1D10C expression — OESOPHAGUS

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