TBC1D10C

Across TCGA cell cohorts, TBC1D10C mutation is significantly associated with the RNA expression of many other genes, with 66 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TBC1D10C-associated genes across cancer lineages are TAAR8, C6orf118, and CCDC105. Each is linked with TBC1D10C in more than 1 cancer types. Because this analysis shows association rather than direction, both TBC1D10C-to-partner and partner-to-TBC1D10C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAAR8 grouped by TBC1D10C-low versus TBC1D10C-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D10C→partner) and Y-score (partner→TBC1D10C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	TAAR8 →	+0.022	+5.662	<.001	.002	3	2
BLOOD_Leukemia	C6orf118 →	+0.029	+2.772	.002	.004	3	2
LUNG_NSCLC_LUAD	CCDC105 →	+0.006	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR8B4 →	+0.034	+4.887	<.001	.009	3	1
BLOOD_Leukemia	C9 →	+0.776	+3.029	<.001	.002	3	1
BLOOD_Leukemia	FAM155B →	+0.496	+3.781	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

TAAR8 by TBC1D10C expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →