TBC1D10B

Across TCGA pan-cancer cohorts, TBC1D10B Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TBC1D10B data layer compared with 25 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher TBC1D10B Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated TBC1D10B expression acts as an unfavorable survival marker.

COAD, DLBC, and MESO are the cancer types where TBC1D10B Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.410	0.795	.011	14	view →
DLBC	OS	Median	All	0.054	0.842	<.001	12	view →
MESO	DFS	Median	II,III,IV	0.039	0.407	<.001	12	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TBC1D10B–COAD (DFS)

Open the COAD breakdown →