TBC1D10B

Across TCGA patient cohorts, TBC1D10B protein abundance is significantly associated with the RNA expression of many other genes, with 6,837 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible TBC1D10B-associated genes across cancer lineages are MAPK3, ZNF689, and CD2BP2. Each is linked with TBC1D10B in more than 4 cancer types. Because this analysis shows association rather than direction, both TBC1D10B-to-partner and partner-to-TBC1D10B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TBC1D10B versus MAPK3 in BRCA, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D10B→partner) and Y-score (partner→TBC1D10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MAPK3 →	+0.537	+0.301	<.001	<.001	3	5
BRCA	ZNF689 →	+0.859	+0.274	.001	.001	3	5
BRCA	CD2BP2 →	+0.473	+0.238	<.001	<.001	3	5
BRCA	DCTPP1 →	+0.630	+0.293	<.001	<.001	3	5
BRCA	CDIPT →	+0.586	+0.239	.001	.002	3	4
LUAD	CEP20 →	+0.396	+0.140	.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,837 associations by consensus.

TBC1D10B vs MAPK3 — BRCA

Explore this scatter interactively →