TBC1D10B

Across TCGA cell cohorts, TBC1D10B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,941 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TBC1D10B-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Interleukin-34-mediated signaling pathway, and Positive regulation of anaphase-promoting complex-dependent catabolic process. Each is linked with TBC1D10B in more than 16 cancer types. Because this analysis shows association rather than direction, both TBC1D10B-to-partner and partner-to-TBC1D10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by TBC1D10B-low versus TBC1D10B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TBC1D10B→partner) and Y-score (partner→TBC1D10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.203	+1.250	<.001	<.001	2	17
OVARY	Interleukin-34-mediated signaling pathway →	+0.202	+0.788	<.001	<.001	3	16
BONE	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.188	+0.959	<.001	<.001	3	15
BREAST	Protein localization to chromatin →	+0.109	+0.769	<.001	.001	3	15
URINARY_TRACT	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.220	+1.395	<.001	<.001	3	15
BREAST	Positive regulation of mitotic cytokinesis →	+0.178	+0.875	.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,941 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by TBC1D10B expression — URINARY_TRACT

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