TAX1BP1

Across TCGA pan-cancer cohorts, TAX1BP1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated TAX1BP1 data layer compared with 22 for mass-spec protein and 2 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher TAX1BP1 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated TAX1BP1 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

BRCA, UCEC, and LIHC are the cancer types where TAX1BP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	II,III,IV	0.287	0.913	<.001	30	view →
UCEC	OS	Median	II,III,IV	0.933	0.318	.012	14	view →
LIHC	DFS	Median	All	0.044	0.553	<.001	12	view →
PRAD	DFS	Median	All	0.085	0.774	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

TAX1BP1–BRCA (OS)

Open the BRCA breakdown →