TAX1BP1

Across TCGA pan-cancer cohorts, TAX1BP1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TAX1BP1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where TAX1BP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TAX1BP1 is over-expressed in tumor, although a few such as UCEC and KICH show the opposite, repressed pattern.

LIHC, LUAD, and BRCA are the cancer types where TAX1BP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TAX1BP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	II,III,IV	+1.248	<.001	9	view →
LUAD	All	III,IV	+0.608	<.001	8	view →
BRCA	All	III,IV	+0.420	<.001	6	view →
KIRP	All	II,III,IV	+0.401	.007	6	view →
CHOL	All	All	+1.713	<.001	5	view →
PAAD	All	All	+0.455	.008	2	view →
UCEC	All	All	−0.410	.021	2	view →
HNSC	Female	III,IV	+0.644	.015	1	view →
ESCA	All	All	+0.573	.044	1	view →
STAD	All	All	+0.372	.042	1	view →
KICH	All	All	−0.304	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TAX1BP1–LIHC

Open the LIHC breakdown →