TAX1BP1

Across TCGA patient cohorts, TAX1BP1 mutation is significantly associated with the RNA expression of many other genes, with 2,052 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAX1BP1-associated genes across cancer lineages are RNU1-57P, RN7SL726P, and LINC00869. Each is linked with TAX1BP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAX1BP1-to-partner and partner-to-TAX1BP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-57P grouped by TAX1BP1-low versus TAX1BP1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAX1BP1→partner) and Y-score (partner→TAX1BP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	RNU1-57P →	+0.676	+5.611	<.001	<.001	3	3
UCEC	RN7SL726P →	+0.180	+2.096	<.001	.001	3	2
UCEC	LINC00869 →	-0.502	-2.145	<.001	.003	3	2
UCEC	SLC7A11 →	+0.712	+3.470	.002	.002	3	2
UCEC	SKA1 →	+0.546	+3.480	.002	.002	3	2
UCEC	SEC13 →	+0.393	+2.617	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,052 associations by consensus.

RNU1-57P by TAX1BP1 expression — STAD

Explore this box plot interactively →