TATDN1

Across TCGA patient cohorts, TATDN1 mutation is significantly associated with the RNA expression of many other genes, with 73 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TATDN1-associated genes across cancer lineages are FTLP18, HMGB3P23, and RNU6-1090P. Each is linked with TATDN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TATDN1-to-partner and partner-to-TATDN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTLP18 grouped by TATDN1-low versus TATDN1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TATDN1→partner) and Y-score (partner→TATDN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FTLP18 →	+0.110	+6.936	<.001	<.001	3	2
HNSC	HMGB3P23 →	+0.118	+5.182	.001	.007	3	2
BLCA	RNU6-1090P →	+0.278	+7.640	<.001	.009	3	2
UCEC	KRTAP23-1 →	+0.277	+3.302	.006	.009	3	2
UCEC	RAB28P2 →	+0.120	+4.400	<.001	.006	3	2
UCEC	RN7SKP277 →	+0.152	+4.400	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

FTLP18 by TATDN1 expression — HNSC

Explore this box plot interactively →