Across TCGA cell cohorts, TAT RNA expression is significantly associated with the go_rna of many other GO terms, with 2,140 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAT-associated GO terms across cancer lineages are External encapsulating structure organization, Muscle organ development, and Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway. Each is linked with TAT in more than 6 cancer types. Because this analysis shows association rather than direction, both TAT-to-partner and partner-to-TAT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAT→partner) and Y-score (partner→TAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	External encapsulating structure organization →	-0.150	-0.053	.003	.004	3	7
LARGE_INTESTINE	Muscle organ development →	-0.036	-0.104	.002	.007	3	7
CNS	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.116	+0.036	<.001	.003	3	6
PANCREAS	Negative regulation of MDA-5 signaling pathway →	+0.145	+0.070	<.001	.006	3	6
LIVER	Fatty acid catabolic process →	+0.095	+0.586	<.001	.005	3	6
KIDNEY	Positive regulation of gene expression, epigenetic →	+0.046	+0.036	.003	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,140 associations by consensus.

Exploration

TAT survival (RNA) · tumor vs normal (RNA) · all TAT data types