TASOR2

Across TCGA cell cohorts, TASOR2 mutation is significantly associated with the RNA expression of many other genes, with 1,055 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TASOR2-associated genes across cancer lineages are OR2D3, GOLGA6L6, and TRIM60. Each is linked with TASOR2 in more than 2 cancer types. Because this analysis shows association rather than direction, both TASOR2-to-partner and partner-to-TASOR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2D3 grouped by TASOR2-low versus TASOR2-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TASOR2→partner) and Y-score (partner→TASOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OR2D3 →	+0.028	+4.930	<.001	.008	3	3
LUNG_NSCLC_LUAD	GOLGA6L6 →	+0.004	+3.813	<.001	.001	3	3
SOFT_TISSUE	TRIM60 →	+0.375	+4.930	<.001	.008	3	2
OESOPHAGUS	OR2A2 →	+0.106	+4.044	<.001	.005	3	2
PANCREAS	TAFA1 →	+0.017	+4.011	.002	.009	3	2
OVARY	SEL1L2 →	+0.043	+3.938	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,055 associations by consensus.

OR2D3 by TASOR2 expression — SOFT_TISSUE

Explore this box plot interactively →