TAS2R8

Across TCGA patient cohorts, TAS2R8 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,473 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TAS2R8-associated proteins across cancer lineages are CDA, EEF2_S502, and FLNB_S1505. Each is linked with TAS2R8 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAS2R8-to-partner and partner-to-TAS2R8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAS2R8 versus CDA in GBM, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R8→partner) and Y-score (partner→TAS2R8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CDA →	-0.776	-0.400	<.001	<.001	3	3
HNSC	EEF2_S502 →	-0.703	-0.306	<.001	<.001	3	3
GBM	FLNB_S1505 →	-0.892	-0.513	.001	.001	3	3
HNSC	JUNB →	-0.378	-0.205	<.001	.009	3	3
GBM	VPS26A →	-0.171	-0.367	<.001	.002	3	3
LSCC	UBL4A_S90 →	+0.492	+0.184	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,473 associations by consensus.

TAS2R8 vs CDA — GBM

Explore this scatter interactively →