TAS2R8

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, TAS2R8 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TAS2R8’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where TAS2R8 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TAS2R8 is over-expressed in tumor.

LIHC and KIRC are the cancer types where TAS2R8 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TAS2R8 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LIHCAllAll+0.007.0134view →
KIRCFemaleAll+0.014.0311view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

TAS2R8–LIHC

Tumor-vs-normal expression box plot for TAS2R8 RNA in LIHC.

Open the LIHC breakdown →

Exploration