TAS2R7

Across TCGA patient cohorts, TAS2R7 mutation is significantly associated with the RNA expression of many other genes, with 2,274 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAS2R7-associated genes across cancer lineages are BNIP3P41, H2AB3, and ESS2. Each is linked with TAS2R7 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAS2R7-to-partner and partner-to-TAS2R7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BNIP3P41 grouped by TAS2R7-low versus TAS2R7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R7→partner) and Y-score (partner→TAS2R7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BNIP3P41 →	+0.011	+4.156	<.001	.004	3	3
SKCM	H2AB3 →	+0.031	+5.495	<.001	<.001	3	2
UCEC	ESS2 →	+0.270	+2.180	.005	.002	3	2
UCEC	CRYBB2P1 →	+0.471	+2.191	.001	.002	3	2
UCEC	CENPM →	+0.554	+3.470	.005	.002	3	2
UCEC	JOSD1 →	+0.410	+2.662	.006	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,274 associations by consensus.

BNIP3P41 by TAS2R7 expression — UCEC

Explore this box plot interactively →