TAS2R7

Across TCGA pan-cancer cohorts, TAS2R7 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated TAS2R7 data layer compared with 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher TAS2R7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TAS2R7 expression acts as an unfavorable survival marker.

LUSC, KIRP, and UCS are the cancer types where TAS2R7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Tertile	II,III,IV	0.222	0.721	<.001	81	view →
KIRP	DFS	Tertile	All	0.517	0.922	<.001	81	view →
UCS	OS	Tertile	III,IV	0.102	0.591	<.001	72	view →
LUAD	OS	Tertile	III,IV	0.163	0.663	.012	36	view →
DLBC	OS	Tertile	All	0.053	0.936	<.001	27	view →
ACC	DFS	Tertile	All	0.089	0.634	.001	18	view →
SKCM	DFS	Tertile	III,IV	0.097	0.655	.001	15	view →
BRCA	OS	Tertile	II,III,IV	0.266	0.579	.022	15	view →
THCA	OS	Tertile	All	0.620	0.931	.013	9	view →
COAD	DFS	Tertile	III,IV	0.170	0.697	.030	9	view →
STAD	DFS	Tertile	IV	0.160	0.402	.044	9	view →
ESCA	OS	Tertile	All	0.505	0.698	.035	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

TAS2R7–LUSC (DFS)

Open the LUSC breakdown →