Across TCGA cell cohorts, TAS2R60 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TAS2R60-associated genes across cancer lineages are CD300H, DEFB125, and C9orf92. Each is linked with TAS2R60 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAS2R60-to-partner and partner-to-TAS2R60 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R60→partner) and Y-score (partner→TAS2R60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CD300H →	+0.045	+5.415	<.001	.004	3	2
LUNG_NSCLC_LUAD	DEFB125 →	+0.017	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	C9orf92 →	+0.141	+4.212	.004	.007	3	1
LUNG_NSCLC_LUAD	USP17L22 →	+0.023	+4.947	<.001	.001	3	1
BLOOD_Lymphoma	PF4V1 →	+0.180	+5.247	<.001	.001	3	1
BLOOD_Lymphoma	NEUROG1 →	+0.004	+4.643	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

TAS2R60 survival (RNA) · tumor vs normal (RNA) · all TAS2R60 data types