Across TCGA patient cohorts, TAS2R50 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,636 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TAS2R50-associated proteins across cancer lineages are NBEAL2, NOP58, and PCIF1. Each is linked with TAS2R50 in more than 3 cancer types. Because this analysis shows association rather than direction, both TAS2R50-to-partner and partner-to-TAS2R50 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R50→partner) and Y-score (partner→TAS2R50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NBEAL2 →	-0.489	-0.723	<.001	<.001	3	3
GBM	NOP58 →	+0.243	+0.444	.004	.004	3	3
GBM	PCIF1 →	+0.337	+0.567	<.001	<.001	3	3
GBM	PHC2 →	+0.335	+0.502	<.001	<.001	3	3
HNSC	TUT7 →	-0.256	-0.656	<.001	<.001	3	3
BRCA	PPFIA3_S683 →	+0.686	+0.145	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,636 associations by consensus.

Exploration

TAS2R50 survival (RNA) · tumor vs normal (RNA) · all TAS2R50 data types