TAS2R50

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TAS2R50 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,417 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TAS2R50-associated GO terms across cancer lineages are Negative regulation of chromosome condensation, Regulation of DNA recombination, and Positive regulation of double-strand break repair. Each is linked with TAS2R50 in more than 9 cancer types. Because this analysis shows association rather than direction, both TAS2R50-to-partner and partner-to-TAS2R50 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R50→partner) and Y-score (partner→TAS2R50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUENegative regulation of chromosome condensation →+0.132+0.078<.001<.001310
SOFT_TISSUERegulation of DNA recombination →+0.058+0.081<.001<.00139
SOFT_TISSUEPositive regulation of double-strand break repair →+0.092+0.121<.001<.00139
SOFT_TISSUEPositive regulation of DNA recombination →+0.064+0.082<.001<.00139
BONERegulation of mRNA splicing, via spliceosome →+0.099+0.103<.001<.00138
SOFT_TISSUEmRNA alternative polyadenylation →+0.072+0.094<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,417 associations by consensus.

Exploration