TAS2R5

Across TCGA patient cohorts, TAS2R5 protein abundance is significantly associated with the RNA expression of many other genes, with 86 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TAS2R5-associated genes across cancer lineages are AREG, CPA4, and GIT2. Each is linked with TAS2R5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAS2R5-to-partner and partner-to-TAS2R5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAS2R5 versus AREG in LSCC, with a Pearson correlation of -0.98.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R5→partner) and Y-score (partner→TAS2R5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AREG →	-0.945	-0.524	.003	.009	2	1
LSCC	CPA4 →	-1.635	-0.524	<.001	.009	2	1
LSCC	GIT2 →	-0.364	-0.524	<.001	.009	2	1
LSCC	OR10A2 →	-1.070	-0.524	.001	.009	2	1
LSCC	TARS3 →	-0.499	-0.524	.008	.009	2	1
LSCC	TLR7 →	-0.814	-0.524	.007	.009	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 86 associations by consensus.

TAS2R5 vs AREG — LSCC

Explore this scatter interactively →