TAS2R5

Across TCGA cell cohorts, TAS2R5 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TAS2R5-associated genes across cancer lineages are SCGB3A2, OR51T1, and GSG1L2. Each is linked with TAS2R5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAS2R5-to-partner and partner-to-TAS2R5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCGB3A2 grouped by TAS2R5-low versus TAS2R5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R5→partner) and Y-score (partner→TAS2R5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SCGB3A2 →	+0.117	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1
BLOOD_Leukemia	GSG1L2 →	+0.058	+5.969	<.001	.001	3	1
BLOOD_Leukemia	OR4A47 →	+0.022	+5.539	<.001	.003	3	1
LARGE_INTESTINE	CST9L →	+0.018	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

SCGB3A2 by TAS2R5 expression — BLOOD_Leukemia

Explore this box plot interactively →