TAS2R31

Across TCGA patient cohorts, TAS2R31 mutation is significantly associated with the RNA expression of many other genes, with 121 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAS2R31-associated genes across cancer lineages are TDGF1P2, LINC01486, and MIR4494. Each is linked with TAS2R31 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAS2R31-to-partner and partner-to-TAS2R31 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TDGF1P2 grouped by TAS2R31-low versus TAS2R31-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R31→partner) and Y-score (partner→TAS2R31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	TDGF1P2 →	+0.073	+5.289	<.001	.003	3	2
BRCA	LINC01486 →	+0.100	+4.255	.001	.008	3	2
BRCA	MIR4494 →	+0.285	+4.760	.003	.007	3	2
BLCA	MTND6P8 →	+0.114	+4.788	<.001	.006	3	2
UCEC	RNA5SP405 →	+0.509	+4.260	<.001	.007	3	2
UCEC	RNA5SP223 →	+0.299	+4.260	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 121 associations by consensus.

TDGF1P2 by TAS2R31 expression — BLCA

Explore this box plot interactively →