TAS2R16

Across TCGA patient cohorts, TAS2R16 mutation is significantly associated with the RNA expression of many other genes, with 1,283 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAS2R16-associated genes across cancer lineages are RNA5SP412, C22orf39, and SNHG30. Each is linked with TAS2R16 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAS2R16-to-partner and partner-to-TAS2R16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by TAS2R16-low versus TAS2R16-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R16→partner) and Y-score (partner→TAS2R16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.554	+2.230	<.001	.005	3	3
UCEC	C22orf39 →	+0.542	+2.828	<.001	.001	3	3
UCEC	SNHG30 →	+0.793	+3.708	<.001	<.001	3	3
BLCA	GAPDHP41 →	+0.094	+4.840	<.001	.002	3	2
BLCA	RNU6-1008P →	+0.484	+4.883	<.001	.002	3	2
STAD	SNORD82 →	+0.846	+3.673	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,283 associations by consensus.

RNA5SP412 by TAS2R16 expression — UCEC

Explore this box plot interactively →