TAS2R13

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TAS2R13 mutation is significantly associated with the RNA expression of many other genes, with 1,235 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAS2R13-associated genes across cancer lineages are MTND4LP20, RNA5SP167, and SPRING1P1. Each is linked with TAS2R13 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAS2R13-to-partner and partner-to-TAS2R13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R13→partner) and Y-score (partner→TAS2R13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAMTND4LP20 →+0.152+6.814<.001<.00133
COADRNA5SP167 →+0.344+4.070.004.00932
COADSPRING1P1 →+0.091+4.399<.001.00632
HNSCMTND5P29 →+0.084+5.435<.001.00532
LUADH4C7 →+0.257+5.044<.001.00932
UCECRNA5SP509 →+0.106+3.736<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,235 associations by consensus.

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