Across TCGA pan-cancer cohorts, TAS2R13 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of TAS2R13’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TAS2R13 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TAS2R13 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

HNSC, LUAD, and THCA are the cancer types where TAS2R13 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TAS2R13 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.046	.025	2	view →
LUAD	Male	III,IV	−0.051	.013	1	view →
THCA	All	All	−0.023	.031	1	view →
KIRC	Male	IV	+0.022	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: TAS2R13 RNA expression & survival · all TAS2R13 data types