Across TCGA patient cohorts, TAS2R13 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAS2R13-associated genes across cancer lineages are PKC-b-II_pS660, TFRC, and ATM. Each is linked with TAS2R13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAS2R13-to-partner and partner-to-TAS2R13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS2R13→partner) and Y-score (partner→TAS2R13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PKC-b-II_pS660 →	-0.358	-3.700	.005	.001	3	2
UCEC	TFRC →	+0.656	+2.999	.007	.035	3	2
UCEC	ATM →	-0.583	-3.000	.005	.036	3	2
UCEC	4E-BP1 →	+0.333	+3.029	.008	.018	3	2
UCEC	Cyclin-E2 →	+0.181	+3.179	.021	.010	3	2
UCEC	EGFR_pY1068 →	-0.271	-2.584	.020	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

TAS2R13 survival (RNA) · tumor vs normal (RNA) · all TAS2R13 data types