TAS1R2

Across TCGA patient cohorts, TAS1R2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,085 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TAS1R2-associated GO terms across cancer lineages are Spindle assembly, Regulation of cell division, and Regulation of mRNA catabolic process. Each is linked with TAS1R2 in more than 8 cancer types. Because this analysis shows association rather than direction, both TAS1R2-to-partner and partner-to-TAS1R2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle assembly grouped by TAS1R2-low versus TAS1R2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAS1R2→partner) and Y-score (partner→TAS1R2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Spindle assembly →	+0.075	+0.025	<.001	<.001	3	9
STAD	Regulation of cell division →	+0.057	+0.025	<.001	<.001	3	9
STAD	Regulation of mRNA catabolic process →	+0.056	+0.032	<.001	<.001	3	9
STAD	Regulatory ncRNA processing →	+0.055	+0.027	<.001	<.001	3	9
STAD	Positive regulation of cell cycle process →	+0.066	+0.021	<.001	<.001	3	9
STAD	Mitotic spindle assembly →	+0.078	+0.023	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,085 associations by consensus.

Spindle assembly by TAS1R2 expression — STAD

Explore this box plot interactively →