TARM1

Across TCGA patient cohorts, TARM1 mutation is significantly associated with the RNA expression of many other genes, with 37 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TARM1-associated genes across cancer lineages are MRGPRX13P, MIR3157, and POTED. Each is linked with TARM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TARM1-to-partner and partner-to-TARM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MRGPRX13P grouped by TARM1-low versus TARM1-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TARM1→partner) and Y-score (partner→TARM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	MRGPRX13P →	+0.341	+5.878	<.001	.002	3	1
LIHC	MIR3157 →	+0.442	+5.033	<.001	.009	3	1
LIHC	POTED →	+0.025	+5.268	<.001	.006	3	1
LIHC	RNU6-696P →	+0.346	+5.268	<.001	.006	3	1
LIHC	MIR920 →	+0.466	+5.268	<.001	.006	3	1
LIHC	RN7SL183P →	+0.153	+5.268	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 37 associations by consensus.

MRGPRX13P by TARM1 expression — LIHC

Explore this box plot interactively →