Across TCGA pan-cancer cohorts, TARM1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TARM1’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where TARM1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TARM1 is over-expressed in tumor.
BRCA and THCA are the cancer types where TARM1 tumor–normal differential expression is most reproducible.