TAOK2

Across TCGA pan-cancer cohorts, TAOK2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TAOK2 data layer compared with 25 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher TAOK2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TAOK2 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where TAOK2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	IV	0.781	0.220	.017	13	view →
PDAC	DFS	Tertile	III,IV	0.311	0.902	.003	10	view →
HNSC	DFS	Quartile	III,IV	0.722	0.946	.009	9	view →
LSCC	OS	Quartile	III,IV	0.377	0.972	.004	5	view →
LUAD	OS	Median	All	0.754	0.971	.008	4	view →
GBM	DFS	Median	All	0.269	0.456	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TAOK2–CCRCC (DFS)

Open the CCRCC breakdown →