TAOK2

Across TCGA patient cohorts, TAOK2 mutation is significantly associated with the RNA expression of many other genes, with 7,202 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAOK2-associated genes across cancer lineages are CDCA2, MCAT, and UFD1. Each is linked with TAOK2 in more than 4 cancer types. Because this analysis shows association rather than direction, both TAOK2-to-partner and partner-to-TAOK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDCA2 grouped by TAOK2-low versus TAOK2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAOK2→partner) and Y-score (partner→TAOK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CDCA2 →	+1.013	+4.261	<.001	<.001	3	5
BLCA	MCAT →	+0.504	+3.481	.001	.002	3	5
UCEC	UFD1 →	+0.356	+1.638	<.001	<.001	3	5
UCEC	GPI →	+0.349	+1.595	.002	<.001	3	5
STAD	SHMT2 →	+0.634	+3.202	.003	.009	3	5
COAD	SKA1 →	+0.886	+3.183	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,202 associations by consensus.

CDCA2 by TAOK2 expression — COAD

Explore this box plot interactively →