TANK

Across TCGA cell cohorts, TANK RNA expression is significantly associated with the go_rna of many other GO terms, with 3,862 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TANK-associated GO terms across cancer lineages are Positive regulation of protein deubiquitination, Regulation of protein deubiquitination, and Positive regulation of peptidase activity. Each is linked with TANK in more than 16 cancer types. Because this analysis shows association rather than direction, both TANK-to-partner and partner-to-TANK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein deubiquitination grouped by TANK-low versus TANK-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TANK→partner) and Y-score (partner→TANK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of protein deubiquitination →	+0.183	+1.176	<.001	<.001	3	17
OVARY	Regulation of protein deubiquitination →	+0.114	+0.536	.002	.004	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of peptidase activity →	+0.227	+0.752	.001	.006	2	12
UPPER_AERODIGESTIVE_TRACT	Protein localization to vacuole →	+0.069	+0.677	.002	.003	3	11
OESOPHAGUS	Cytoplasmic pattern recognition receptor signaling pathway →	+0.082	+0.905	<.001	<.001	3	11
LUNG_SCLC	Growth plate cartilage chondrocyte proliferation →	+0.277	+0.647	.009	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,862 associations by consensus.

Positive regulation of protein deubiquitination by TANK expression — BLOOD_Myeloma

Explore this box plot interactively →