Across TCGA patient cohorts, TANGO2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,114 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TANGO2-associated genes across cancer lineages are MEOX2, FOXM1, and NEK2. Each is linked with TANGO2 in more than 6 cancer types. Because this analysis shows association rather than direction, both TANGO2-to-partner and partner-to-TANGO2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TANGO2→partner) and Y-score (partner→TANGO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MEOX2 →	+1.001	+0.291	.001	<.001	3	7
GBM	FOXM1 →	-1.004	-0.387	<.001	<.001	3	7
UCEC	NEK2 →	-1.191	-0.314	<.001	<.001	3	7
BRCA	AOC3 →	+1.450	+0.403	<.001	<.001	3	7
HNSC	ABCA8 →	+1.083	+0.295	<.001	<.001	3	7
HNSC	FLI1 →	+0.724	+0.361	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,114 associations by consensus.

Exploration

TANGO2 survival (RNA) · tumor vs normal (RNA) · all TANGO2 data types