TAMALIN

Across TCGA patient cohorts, TAMALIN mutation is significantly associated with the RNA expression of many other genes, with 195 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAMALIN-associated genes across cancer lineages are SMIM34B, RNU6-992P, and RN7SL248P. Each is linked with TAMALIN in more than 2 cancer types. Because this analysis shows association rather than direction, both TAMALIN-to-partner and partner-to-TAMALIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SMIM34B grouped by TAMALIN-low versus TAMALIN-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAMALIN→partner) and Y-score (partner→TAMALIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SMIM34B →	+0.029	+7.816	<.001	.008	3	3
COAD	RNU6-992P →	+0.422	+7.741	<.001	.009	3	2
UCEC	RN7SL248P →	+0.105	+4.137	<.001	<.001	3	2
BRCA	RNA5SP369 →	+0.347	+6.866	<.001	<.001	3	2
BRCA	RBM22P7 →	+0.073	+8.057	<.001	.005	3	2
UCEC	RNF19BPY →	+0.028	+4.738	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 195 associations by consensus.

SMIM34B by TAMALIN expression — SKCM

Explore this box plot interactively →