TALDO1

Across TCGA pan-cancer cohorts, TALDO1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated TALDO1 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher TALDO1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TALDO1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

LSCC, LUAD, and CCRCC are the cancer types where TALDO1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Quartile	II,III,IV	0.927	0.490	.017	9	view →
LUAD	DFS	Quartile	III,IV	0.498	0.995	.016	3	view →
CCRCC	DFS	Tertile	III,IV	0.450	0.775	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

TALDO1–LSCC (DFS)

Open the LSCC breakdown →