TAGLN2

Across TCGA cell cohorts, TAGLN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,335 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TAGLN2-associated GO terms across cancer lineages are Regulation of proteolysis, Wound healing, and Integrin-mediated signaling pathway. Each is linked with TAGLN2 in more than 11 cancer types. Because this analysis shows association rather than direction, both TAGLN2-to-partner and partner-to-TAGLN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of proteolysis grouped by TAGLN2-low versus TAGLN2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAGLN2→partner) and Y-score (partner→TAGLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of proteolysis →	+0.129	+2.162	<.001	<.001	3	12
BONE	Wound healing →	+0.122	+1.782	<.001	<.001	3	12
BONE	Integrin-mediated signaling pathway →	+0.264	+2.161	<.001	<.001	3	12
BONE	Response to hypoxia →	+0.064	+2.116	<.001	<.001	3	12
BONE	Coagulation →	+0.123	+2.151	<.001	<.001	3	12
BONE	Blood coagulation →	+0.123	+2.151	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,335 associations by consensus.

Regulation of proteolysis by TAGLN2 expression — BONE

Explore this box plot interactively →