TAGLN

Across TCGA patient cohorts, TAGLN RNA expression is significantly associated with the protein abundance of many other proteins, with 21,954 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TAGLN-associated proteins across cancer lineages are PRKG1, RAI14, and VCL. Each is linked with TAGLN in more than 9 cancer types. Because this analysis shows association rather than direction, both TAGLN-to-partner and partner-to-TAGLN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TAGLN versus PRKG1 in UCEC, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TAGLN→partner) and Y-score (partner→TAGLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRKG1 →	+0.864	+1.884	<.001	<.001	3	10
UCEC	RAI14 →	+0.501	+2.008	<.001	<.001	3	10
UCEC	VCL →	+0.686	+2.407	<.001	<.001	3	10
OV	VCL_S795 →	+0.950	+1.507	<.001	<.001	3	10
OV	TAGLN_S166 →	+1.486	+1.368	<.001	<.001	3	10
COAD	TPM1 →	+0.877	+1.371	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,954 associations by consensus.

TAGLN vs PRKG1 — UCEC

Explore this scatter interactively →