TAGLN

Across TCGA cell cohorts, TAGLN RNA expression is significantly associated with the go_rna of many other GO terms, with 4,564 significant associations in total. BONE shows the largest number of these associations.

The most reproducible TAGLN-associated GO terms across cancer lineages are Muscle organ development, Negative regulation of cell-substrate junction organization, and Protein targeting to membrane. Each is linked with TAGLN in more than 9 cancer types. Because this analysis shows association rather than direction, both TAGLN-to-partner and partner-to-TAGLN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Muscle organ development grouped by TAGLN-low versus TAGLN-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TAGLN→partner) and Y-score (partner→TAGLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Muscle organ development →	+0.117	+4.708	<.001	<.001	3	10
BONE	Negative regulation of cell-substrate junction organization →	+0.107	+4.438	.001	<.001	3	10
BONE	Protein targeting to membrane →	+0.085	+5.850	<.001	<.001	3	10
BLOOD_Myeloma	Positive regulation of protein K48-linked ubiquitination →	+0.153	+0.952	.006	.007	3	10
BREAST	Protein activation cascade →	+0.324	+2.855	<.001	<.001	3	9
BONE	Regulation of fibrinolysis →	+0.450	+5.980	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,564 associations by consensus.

Muscle organ development by TAGLN expression — BONE

Explore this box plot interactively →