Across TCGA cell cohorts, TAFA5 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TAFA5-associated genes across cancer lineages are WFDC6, TBC1D3, and CLEC18C. Each is linked with TAFA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both TAFA5-to-partner and partner-to-TAFA5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAFA5→partner) and Y-score (partner→TAFA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	WFDC6 →	+0.050	+4.887	<.001	.009	3	1
LARGE_INTESTINE	TBC1D3 →	+0.043	+2.688	.007	.008	3	1
LARGE_INTESTINE	CLEC18C →	+0.150	+3.555	.001	.003	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

TAFA5 survival (RNA) · tumor vs normal (RNA) · all TAFA5 data types