TAF8

Across TCGA pan-cancer cohorts, TAF8 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated TAF8 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher TAF8 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated TAF8 expression acts as an unfavorable survival marker, although some lineages such as LSCC and CCRCC show a favorable association.

LSCC, HNSC, and CCRCC are the cancer types where TAF8 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.861	0.512	.003	34	view →
HNSC	DFS	Quartile	IV	0.603	0.944	.006	9	view →
CCRCC	OS	Median	III,IV	0.985	0.237	.017	6	view →
OV	DFS	Median	All	0.840	1.000	.020	4	view →
UCEC	DFS	Median	All	1.000	0.936	.023	4	view →
LUAD	DFS	Quartile	II,III,IV	0.837	0.425	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

TAF8–LSCC (DFS)

Open the LSCC breakdown →