TAF8

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TAF8 mutation is significantly associated with the RNA expression of many other genes, with 657 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TAF8-associated genes across cancer lineages are MIR147A, RNU7-128P, and CTBP2P9. Each is linked with TAF8 in more than 2 cancer types. Because this analysis shows association rather than direction, both TAF8-to-partner and partner-to-TAF8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR147A grouped by TAF8-low versus TAF8-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TAF8→partner) and Y-score (partner→TAF8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADMIR147A →+0.650+4.893<.001.00533
BLCARNU7-128P →+0.828+3.982<.001.00632
BLCACTBP2P9 →+0.102+4.704<.001.00532
BLCAPISRT1 →+0.052+4.314.004.00932
COADRNU6-693P →+0.463+5.721<.001.00132
UCECNFE2 →-1.065-3.584.002.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 657 associations by consensus.

MIR147A by TAF8 expression — COAD

Box plot of MIR147A in TAF8-low vs TAF8-high samples in COAD.

Explore this box plot interactively →

Exploration